Iron deficiency in sickle cell anaemia.

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Iron deficiency anaemia in sickle cell disorders in India.

BACKGROUND & OBJECTIVE Iron deficiency anaemia (IDA) is uncommon in individuals with sickle cell disease (SCD) because of availability of an adequate iron source potentially from increased red cell turnover and from blood transfusions. Also, iron deficiency anaemia can often go unnoticed because the sickle cell disease patients are already anaemic. Iron deficiency in sickle cell patients may re...

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Iron Deficiency Anaemia among Pre-School Children with Sickle Cell Anaemia: Still a Rare Diagnosis?

BACKGROUND The frequent need for blood transfusion in children with SCA creates the impression that IDA is rare in this class of children. OBJECTIVES The objective of the study is to determine the prevalence of IDA in a population of under-five children with SCA in Lagos, Nigeria. METHODOLOGY Serum iron, total iron binding capacity, transferrin saturation and serum ferritin were assayed in ...

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Iron deficiency in sickle cell anemia.

Thirty-seven patients with SCD were studied: 24 were diagnosed as homozygous Hb S on the basis of their haematological findings, and alpha:non-alpha globin chain ratios were found to be balanced in all. Thirteen patients were thought to have alpha or beta thalassaemia interaction with Hb S on the basis of low MCV and MCH, family history and/or presence of Hb A on electrophoresis. Six of them ha...

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Iron deficiency anaemia in Jamaican children, aged 1-5 years, with sickle cell disease.

OBJECTIVE The aim of this study was to determine, using a combination of measures, the prevalence of iron deficiency anaemia (IDA) in children under five years-of-age who have sickle cell disease (SCD) and attend the Sickle Cell Clinic (SCU) of the Tropical Medicine Research Institute. MATERIALS AND METHODS Children with homozygous sickle cell anaemia (Hb SS) or doubly heterozygous for Hb S a...

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Hepatopulmonary syndrome associated with iron overload in sickle cell anaemia.

At present, it is estimated that 10,000 to 20,000 patients in the USA are treated with long-term blood transfusion [1], including patients with sickle cell disease (SCD) who are often transfused to prevent stroke [2, 3]. Iron overload is common in patients with recurrent transfusion, and the degree of iron overload may correlate with the rate of transfusions [4, 5]. While iron overload and cirr...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1983

ISSN: 0021-9746

DOI: 10.1136/jcp.36.9.1012